| |
|
Capabilities
With our fully integrated LENS™ (Lead Evolution via Novel Synergies) Technology, you'll benefit from wide-ranging Fragment-based Lead Discovery (FBLD) expertise aimed at producing high-quality leads quickly.
- Libraries
- 800-compound collection chosen by structure-based drug discovery experts
- Synthetically accessible compounds
- Combination of readily accessible cores and novel Intellectual Property (IP)
- X-ray Crystallographic Screening
- Expertise with screening and structural determination of difficult drug targets
- Fully automated
- ACTOR™ crystal transfer/data collection
- MIExpert structure solution
- Complementary Screening
- Surface Plasmon Resonance
- Calorimetry
- Chemistry
- Parallel synthesis capabilities
- Rapid structure-guided lead optimization
- Early Lead through GMP manufacturing
- Pre-clinical development
- In vitro and in vivo assays
- Formulation and measurement of physicochemical properties
|