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Capabilities
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Structural Biology
LENS™ Technology
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Capabilities

With our fully integrated LENS™ (Lead Evolution via Novel Synergies) Technology, you'll benefit from wide-ranging Fragment-based Lead Discovery (FBLD) expertise aimed at producing high-quality leads quickly.

  • Libraries
    • 800-compound collection chosen by structure-based drug discovery experts
    • Synthetically accessible compounds
    • Combination of readily accessible cores and novel Intellectual Property (IP)
  • X-ray Crystallographic Screening
    • Expertise with screening and structural determination of difficult drug targets
    • Fully automated
      • ACTOR™ crystal transfer/data collection
      • MIExpert structure solution
  • Complementary Screening
    • Surface Plasmon Resonance
    • Calorimetry
  • Chemistry
    • Parallel synthesis capabilities
    • Rapid structure-guided lead optimization
    • Early Lead through GMP manufacturing
  • Pre-clinical development
    • In vitro and in vivo assays
    • Formulation and measurement of physicochemical properties


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