Ipamorelin

Ipamorelin

Ipamorelin is a peptide and a growth hormone secretagogue and it is quite popular for its safety. Ipamorelin is actually known for its cleanliness and safeness in the world of GHRP’s. In addition to this, ipamorelin does not entail the side-effect of elevated hunger like other GHRP’s.

In fact, ipamorelin has a lot going for it compared to other GHRP’s.Clinical research studies have shown that Ipamorelin can help to increase LBM (lean body mass) and lower body fat. These studies have also shown that Ipamorelin can help to improve sleep and mood as well without any spike in cortisol or prolactin, when administered at lower doses.

Despite the fact that scientists know more about ipamorelin than other peptides, research has not ceased to be pursued. According to the University of Queensland School of Medicine Ochsner Clinical School, ipamorelin has been shown to aid in the management of postoperative ileus in bowel resection patients. In this study, Ipamorelin was shown to be tolerable as taken twice daily for seven days.Learn more additional details at https://www.peptidesciences.com/ipamorelin

Although there was no significant difference between that of the ipamorelin and the placebo, there were signs that ipamorelin possesses attributes that could be tested further with more positive results.

Another study conducted by the University of Aarhus showed some more promising results. A group of 8-month-old female rats underwent ipamorelin injections three times daily for 3 months. After this test time, ipamorelin showed to counteract the effects of glucocorticoid on skeletal muscles as well as bones.Basically, ipamorelin showed to be a great aid in reversing the effects of decreased muscle strength and bone deformation.

Ipamorelin

Anderson, N.B., et al. “Regular Article: The Growth Hormone Secretagogue Ipamorelin Counteracts Glucocorticoid-Induced Decrease in Bone Formation of Adult Rats.” Growth Hormone & IGF Research 11.(2001): 266-272. ScienceDirect. Web. 15 July 2016.

Beck, David E, Brian Sweeney, and Martin D McCarter. “Prospective, Randomizes, Controlled, Proof-of-Concept Study of the Ghrelin Mimetic Ipamorelin for the Management of Prosoperative Ileus in Bowel Resection Patients.” International Journal of Colorectal Disease. 29.12 (2014): 1527-1534. Webline. 15 July 2016.

KB. “iPamorelin Facts Explained.” Evolutionary.org. Web. 15 July 2016.… Read the rest...

What is IGF1-LR3

IGF1-LR3

IGF1-LR3 is a polypeptide that possesses a lot of the same qualities as insulin. In fact, IGF actually stands for insulin-like growth factor. IGF1-LR3. This particular peptide is known for its effect on bone growth.See this article to get more updates.

There have been plenty of studies involving this popular peptide. One of these studies, conducted by Lund University Hospital, involved a continuous application of IGF1-LR3 with a mini pump. The focus of application was on a healing bone callus on a rabbit’s tibia. Results showed that this reduced the mineral turnover rate. However, it showed no change in the amount of bone mineral. It was concluded that these bone mineral levels were already optimized for proper healing.

In addition to this, muscle growth can also be affected by IGF1-LR3, as shown in a study conducted by the University of Sao Paulo. Bone and muscle growth was study in rats who underwent applications of IGF1-LR3 and the results showed that this insulin-like substance promotes a reduced secretion of the anabolic hormones as well as lower synthesis of proteoglycans. This change lead to an impairment of total body growth and the growth of the tissues that were analyzed.

Another study, conducted by the Mount Sinai School of Medicine, showed that this insulin-like peptide can establish normal body and organ size. However, overuse or uncontrolled use of IGF1-LR3 can lead to pathological conditions.

There is still much to learn about IGF1-LR3 and studies will continue to take place. With mixed results, it is difficult to say how this peptide may be utilized in the future and whether or not it will be available for humans to use.

IGF1-LR3

Aspenberg P, Albrektsson T, and Thorngren KG, “Local Application of Growth-Factor IGF-1 to Healing Bone. Experiments with a Titanium Chamber in Rabbits.” PubMed. 1989. Web. 29 July 2016.Need more information? go to https://en.wikipedia.org/wiki/Insulin-like_growth_factor_1

Sebastien, Elis. “Unbound (bioavailable) IGF! Enhances Somatic Growth.” Disease Models & Mechanisms. 2011. Web. 19 July 2016.

Star, Russian. “IGF1-LR3 the Anabolic Powerhouse.” Evolutionary. Web. 19 July 2016.

Tirapegui J. “Effect of Insulin-Like Growth Factor-1 (IGF-1) on Muscle and Bone Growth in Experimental Models.” PubMed. 1999. Web. 19 July 2016.

.… Read the rest...